Dengel co-author on article published in the Journal of Applied Physiology

Don Dengel, PhD, professor in the School of Kinesiology and director of the Laboratory of Integrative Human Physiology (LIHP), is a co-author of an article published in the Journal of Applied Physiology. The article titled, “Endothelial-derived extracellular vesicles associated with electronic cigarette use impair cerebral microvascular cell function,” examined the effect of circulating endothelial cell-derived microvesicles isolated from e-cigarette users on human cerebral microvascular endothelial cells, nitric oxide and endothelin-1 production and tissue-type plasminogen activator release. This research suggests that endothelial cell-derived microvesicles are a potential mediating factor in the increased risk of stroke associated with e-cigarette use.

The article has been selected for APSselect, a monthly collection from the American Physiological Society that showcases some of the best recently published articles in physiological research. Nick Evanoff, MS, a current doctoral student in the School of Kinesiology was also co-author on this article.